Head Neck Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
sentinel lymph node biopsy
Surgical technique to identify and remove the first lymph node draining a tumor site.
pyriform sinus
Lateral recess of hypopharynx; common site of hypopharyngeal cancer with tendency for submucosal spread.
radial forearm free flap
Microvascular free flap based on the radial artery, commonly used for oral cavity reconstruction. Also known as the Chin...
radical neck dissection
Surgical removal of all lymph node groups in the neck along with surrounding structures including muscle and nerve.
recurrent laryngeal nerve
Branch of the vagus nerve that innervates most intrinsic laryngeal muscles; injury causes vocal cord paralysis.
retromolar trigone
Triangular area of tissue behind the last mandibular molar, a common site for oral cavity cancers.
retropharyngeal lymph nodes
Deep cervical lymph nodes located in the retropharyngeal space between the pharynx and prevertebral fascia. First echelo...
salvage laryngectomy
Total laryngectomy performed after failure of primary nonsurgical treatment. Carries higher morbidity than primary surge...
salvage surgery
Surgical intervention performed after failure of primary non-surgical treatment.
segmental mandibulectomy
Surgical removal of a continuous segment of the mandible including the tooth-bearing portion. Distinguished from margina...
selective neck dissection
Surgical removal of specific lymph node groups in the neck while preserving non-lymphatic structures.
sentinel lymph node biopsy
Surgical technique to identify and remove the first lymph node draining a tumor site.
sinonasal undifferentiated carcinoma
An aggressive malignancy of the nasal cavity and paranasal sinuses characterized by poorly differentiated cells.
spinal accessory nerve
Eleventh cranial nerve innervating trapezius muscle; injury during neck dissection causes shoulder dysfunction.
squamous cell carcinoma
The most common type of head and neck cancer, arising from the flat cells lining the mucous membranes.
superior laryngeal nerve
Branch of vagus nerve with internal and external divisions; controls cricothyroid muscle and laryngeal sensation.
supracricoid laryngectomy
Partial laryngectomy preserving the cricoid cartilage and at least one arytenoid cartilage. A conservative surgical opti...
supraglottic laryngectomy
Surgical removal of the portion of the larynx above the vocal cords, preserving voice function while treating cancer.
thyroglossal duct cyst
Congenital cystic mass arising from embryonic thyroglossal duct remnants, typically presenting in the midline neck.
thyroid cartilage invasion
Tumor penetration through thyroid cartilage, upstaging laryngeal cancer to T4a classification.
TNM staging
Standardized cancer staging system evaluating tumor size (T), nodal involvement (N), and distant metastases (M).
transoral robotic surgery
Minimally invasive surgical technique using robotic assistance for head and neck procedures via the oral cavity. Abbrevi...
trismus
Restricted mouth opening due to muscle fibrosis or spasm, often following head and neck cancer treatment.
vallecular cyst
Benign cyst occurring in the vallecula between the epiglottis and tongue base. Can cause dysphagia or airway obstruction...
velopharyngeal insufficiency
Incomplete closure of the soft palate against the posterior pharyngeal wall, resulting in speech and swallowing difficul...