Neuromuscular Medicine Glossary

Diagnostic test measuring electrical activity in muscles to assess neuromuscular function.

Spontaneous, low-amplitude electrical activity recorded from the muscle endplate region during electromyography. Represe...

Abnormal electrical communication between adjacent nerve fibers due to demyelination, causing inappropriate activation o...

A late electrophysiological response representing backfiring of motor neurons, used to assess proximal nerve conduction...

Selective wasting of individual muscle fascicles creating a scalloped muscle border appearance. Indicates chronic denerv...

A minimally invasive nerve biopsy technique targeting individual fascicles while preserving nerve function.

Involuntary muscle twitching visible under the skin, often indicating motor neuron disease.

Spontaneous electrical discharge from a motor unit visible as brief muscle twitches, often indicating motor neuron disea...

Spontaneous electrical activity from denervated muscle fibers, appearing as small diphasic potentials on EMG.

A characteristic maneuver where patients use their hands to 'climb up' their legs when rising from floor to standing, in...

An electrically evoked reflex response used in nerve conduction studies to assess the integrity of the afferent and effe...

Simple bedside test applying cold to ptotic eyelids to temporarily improve ptosis in myasthenia gravis patients, exploit...

Progressive inflammatory myopathy characterized by weakness of distal and proximal muscles with distinctive pathological...

An increase in compound motor action potential amplitude with repetitive nerve stimulation at high frequencies. Characte...

Brief electrical discharges produced by mechanical stimulation during needle electrode insertion into muscle.

Intravenous Immunoglobulin. A blood product therapy used to treat various autoimmune neuromuscular conditions including...

A quantitative measure of neuromuscular transmission variability in single-fiber electromyography, calculated from conse...

Variability in neuromuscular transmission timing measured during single-fiber electromyography, reflecting neuromuscular...

A presynaptic neuromuscular disorder causing weakness that improves with exercise, often associated with malignancy.

Spontaneous small electrical potentials recorded at the neuromuscular junction representing single acetylcholine vesicle...

Muscle disorders caused by defects in mitochondrial function, characterized by exercise intolerance, weakness, and often...

Specialized region of muscle fiber membrane where motor neuron terminals form synapses, constituting the postsynaptic co...

A group of progressive degenerative disorders affecting motor neurons in the brain and spinal cord.

The skin surface location where electrical stimulation most effectively activates a muscle with minimal current. Anatomi...