Neurosurgical Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
bevacizumab
Monoclonal antibody targeting VEGF used as anti-angiogenic therapy for recurrent glioblastoma.
5-ALA fluorescence
A surgical technique using 5-aminolevulinic acid to induce tumor tissue fluorescence, enhancing visualization during gli...
anaplastic astrocytoma
A WHO grade III malignant glial tumor characterized by increased cellularity and nuclear atypia compared to lower-grade...
awake craniotomy
A neurosurgical procedure performed while the patient is conscious to allow real-time testing of brain function during t...
bevacizumab
Monoclonal antibody targeting VEGF used as anti-angiogenic therapy for recurrent glioblastoma.
biopsy-only procedure
A neurosurgical approach where only tissue sampling is performed without attempt at tumor resection, typically for deep...
blood-brain barrier
A selective barrier that prevents most substances in blood from entering brain tissue, critical in brain tumor treatment...
brainstem glioma
Primary brain tumor arising within the brainstem structures, often requiring specialized treatment approaches.
butterfly glioma
A glioma that crosses the midline through the corpus callosum, creating a bilateral symmetric appearance.
carmustine wafer
Biodegradable polymer wafer containing chemotherapy agent placed directly into the tumor cavity during surgery.
cerebellar mutism
Temporary loss of speech following posterior fossa surgery, characterized by inability to speak despite intact comprehen...
cerebellar mutism syndrome
Post-operative complication following posterior fossa surgery characterized by speech loss and behavioral changes.
cerebrospinal fluid
Clear fluid that circulates within the brain ventricles and subarachnoid space, providing cushioning and metabolic suppo...
choroid plexus papilloma
A benign WHO grade I tumor arising from the choroid plexus epithelium, most commonly occurring in the lateral ventricles...
contrast enhancement
Increased signal intensity on post-contrast imaging indicating blood-brain barrier disruption or increased vascularity i...
convection-enhanced delivery
A drug delivery technique using positive pressure to distribute therapeutics directly into brain tissue, bypassing the b...
corpus callosotomy
Surgical division of the corpus callosum to treat certain types of intractable epilepsy or remove callosal tumors.
cortical stimulation mapping
Intraoperative technique using electrical stimulation to identify and preserve critical brain areas during tumor resecti...
craniotomy
A surgical procedure involving the temporary removal of a bone flap from the skull to access the brain.
cytoreduction
Surgical reduction of tumor burden to improve treatment efficacy and patient outcomes.
cytoreductive surgery
Surgical removal of as much tumor tissue as possible to reduce tumor burden and enhance effectiveness of adjuvant therap...
diffusion tensor imaging
Advanced MRI technique that maps white matter fiber tracts to guide surgical planning and minimize functional damage.
DIPG
An aggressive brainstem tumor primarily affecting children with poor prognosis and limited treatment options.
DNT
A benign, cortical tumor typically presenting with seizures in children and young adults.
dural-based tumor
A neoplasm that originates from or is attached to the dura mater, the tough outer membrane covering the brain and spinal...