Thoracic Oncology Glossary

Displacement of mediastinal structures away from midline, indicating volume changes in thoracic cavity.

A minimally invasive surgical procedure to examine and biopsy lymph nodes in the mediastinum for cancer staging.

A rare, aggressive malignancy arising from the mesothelial cells lining the pleura, peritoneum, or pericardium.

A genetic alteration affecting the MET gene that results in increased protein stability and tumor growth, targetable wit...

Comprehensive genetic analysis of tumor tissue to identify targetable mutations and guide precision therapy.

A multidisciplinary meeting focused on interpreting complex genomic testing results and developing personalized treatmen...

A treatment approach combining two or more therapeutic modalities such as surgery, chemotherapy, and radiation therapy.

Treatment given before primary surgical intervention to reduce tumor size and improve surgical outcomes.

A rare chromosomal rearrangement involving the neuregulin-1 gene, found in a small subset of lung adenocarcinomas and po...

Non-small cell lung cancer, the most common type of lung cancer encompassing adenocarcinoma, squamous cell, and large ce...

A rare chromosomal rearrangement involving neurotrophic receptor tyrosine kinase genes, found in lung cancers and target...

A state of limited metastatic cancer burden, typically involving five or fewer metastatic sites, potentially curable wit...

Surgical approach combining oncological resection with plastic surgical reconstruction to optimize both cancer control a...

Lung cancer arising in the superior sulcus that invades adjacent structures, causing characteristic neurological symptom...

Surgical procedure creating a small opening beside the sternum to access anterior mediastinal structures for biopsy or s...

The outer layer of pleura that lines the chest wall and diaphragm in thoracic oncology contexts.

Cancer staging based on histopathological examination of resected tumor specimens and lymph nodes.

The level of programmed death-ligand 1 protein on tumor cells, used to predict response to immunotherapy.

A standardized measure of a patient's functional capacity and ability to carry out daily activities, crucial for treatme...

A surgical procedure creating an opening in the pericardium to drain fluid and prevent recurrent pericardial effusion in...

Tissue sampling procedure to obtain pleural specimens for histopathological diagnosis of pleural disease.

Abnormal accumulation of fluid in the pleural space, commonly associated with lung cancer and requiring drainage.

Therapeutic procedure to prevent recurrent pleural effusions by creating adhesions between visceral and parietal pleura.

Complete surgical removal of an entire lung, typically performed for extensive lung cancer or severe lung disease.