Thoracic Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
ECOG performance status ECOG
A standardized scale (0-5) used to assess a cancer patient's functional status and ability to tolerate treatment.
pneumonitis
Inflammation of lung tissue that can occur as a side effect of radiation therapy or immunotherapy in thoracic oncology p...
postoperative air leak
Persistent escape of air from the lung surface through chest tubes after thoracic surgery. Common complication requiring...
pulmonary nodule
A round or oval-shaped opacity in the lung up to 3 cm in diameter, requiring evaluation for malignancy.
RECIST criteria
Response Evaluation Criteria in Solid Tumors, standardized guidelines for measuring treatment response in cancer patient...
RET rearrangement
A chromosomal translocation involving the RET gene found in lung adenocarcinomas, creating fusion proteins targetable wi...
ROS1 rearrangement
A rare genetic alteration found in lung adenocarcinoma that predicts response to specific targeted therapies.
sarcopenia
Loss of skeletal muscle mass and strength, recognized as an important prognostic factor in thoracic oncology patients.
SBRT
Stereotactic Body Radiation Therapy, a precise high-dose radiation technique for small tumors, also called SABR.
SCLC
Small cell lung cancer, an aggressive neuroendocrine tumor with rapid growth and early metastatic spread.
segmentectomy
Surgical removal of a pulmonary segment, a lung-sparing procedure for small peripheral tumors or patients with limited p...
sleeve resection
Surgical technique that removes a segment of bronchus along with the tumor while preserving lung parenchyma. Also called...
squamous cell carcinoma
A type of non-small cell lung cancer arising from the squamous epithelial cells lining the airways.
subcarinal lymph nodes
Lymph nodes located beneath the carina, important staging structures in lung cancer that require careful assessment.
superior vena cava syndrome
Clinical syndrome caused by compression or obstruction of the superior vena cava, often by thoracic malignancies.
targeted therapy
Precision cancer treatment directed at specific molecular targets or genetic mutations in tumor cells.
thoracentesis
Minimally invasive procedure to remove fluid from the pleural space for diagnostic or therapeutic purposes.
thoracic duct
Major lymphatic vessel in the chest that can be injured during thoracic surgery, leading to chylothorax.
thoracic epidural anesthesia
Regional anesthesia technique placing medication into the thoracic epidural space for pain control during and after thor...
thoracotomy
A surgical incision through the chest wall to access thoracic organs, commonly used for lung cancer resection.
thymic tumor
A rare neoplasm arising from the thymus gland in the anterior mediastinum, including thymomas and thymic carcinomas.
TNM staging
The internationally standardized system for describing the extent of cancer spread using tumor size, lymph nodes, and me...
tumor board
Multidisciplinary team meeting where cancer specialists review patient cases to develop optimal treatment plans. Also ca...
tumor microenvironment
The cellular and molecular environment surrounding a tumor, including immune cells, fibroblasts, blood vessels, and sign...
VATS
Video-Assisted Thoracoscopic Surgery, a minimally invasive approach using small incisions and camera guidance.