Cardiovascular Research Glossary

A statistical analysis method that includes only participants who completed the study according to the protocol requirem...

A statistical calculation that determines the sample size needed to detect a clinically meaningful treatment difference...

The main outcome measure in a clinical trial, used to determine sample size and assess treatment efficacy.

Computer-assisted analysis technique providing precise measurements of coronary artery dimensions from angiographic imag...

Extension of the corrected QT interval on electrocardiogram beyond normal limits, indicating delayed cardiac repolarizat...

Randomized controlled trial, the gold standard study design for evaluating cardiovascular interventions.

The diameter of a coronary artery segment adjacent to but unaffected by stenotic disease, used as a baseline measurement...

Surgical or interventional procedures to restore blood flow to ischemic myocardium, including PCI and CABG.

Sodium-glucose cotransporter-2 inhibitors, antidiabetic drugs that have shown cardiovascular benefits in heart failure t...

Electrocardiographic finding indicating acute transmural myocardial ischemia, diagnostic criterion for STEMI when meetin...

A type of heart attack characterized by complete blockage of a coronary artery, identified by ST-segment elevation on el...

Formation of blood clot within or adjacent to a previously implanted coronary stent, potentially leading to acute vessel...

A measurable outcome that substitutes for a clinically meaningful endpoint and is reasonably likely to predict clinical...

An updated risk stratification tool that combines anatomical complexity with clinical variables to predict mortality aft...

A standardized angiographic grading tool used to quantify the complexity and extent of coronary artery disease.

Composite endpoint encompassing cardiac death, target vessel myocardial infarction, or target lesion revascularization,...

Any repeat revascularization procedure involving the originally treated lesion or within 5mm of its margins.

Composite endpoint including cardiac death, target vessel-related myocardial infarction, or target vessel revascularizat...

Any repeat percutaneous or surgical intervention involving the specific coronary vessel that was treated in the index pr...

Minimally invasive procedure replacing a stenotic aortic valve via catheter-based delivery, avoiding open-heart surgery.

A therapeutic approach using clot-dissolving medications to restore blood flow in coronary arteries during acute myocard...

Statistical methodology examining the time until occurrence of a specific event, accommodating censored data in cardiova...

Standardized angiographic grading system (0-3) for assessing coronary artery perfusion during cardiac catheterization.

Target lesion revascularization representing repeat intervention at the previously treated coronary segment driven by an...