Cardiovascular Research Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
coronary microvascular dysfunction CMD
Impaired function of small coronary vessels (<500 μm) that cannot be visualized on conventional angiography, causing ischemia despite normal epicardial arteries.
intravascular ultrasound
Catheter-based imaging technique providing cross-sectional views of coronary vessel architecture from within the arteria...
IVUS
Invasive imaging modality using ultrasound to visualize coronary artery wall structure and guide interventional procedur...
Kaplan-Meier curve
A statistical method for displaying time-to-event data, showing the probability of survival or event-free survival over...
late lumen loss
The difference between immediate post-procedural minimal lumen diameter and minimal lumen diameter at follow-up angiogra...
late stent thrombosis
Thrombotic occlusion of a coronary stent occurring between 30 days and 1 year after implantation, representing delayed h...
LVEF
A key cardiac function measurement expressed as a percentage of blood pumped out of the left ventricle with each heartbe...
MACCE
Major adverse cardiac and cerebrovascular events, an expanded composite endpoint including stroke alongside traditional...
MACE
A composite endpoint commonly used in cardiovascular trials, typically including cardiovascular death, myocardial infarc...
minimal luminal diameter
The narrowest point of a coronary artery segment as measured by quantitative coronary angiography.
myocardial blush grade
An angiographic assessment of microvascular perfusion that evaluates tissue-level reperfusion beyond epicardial coronary...
myocardial contrast echocardiography
An imaging technique using microbubble contrast agents to assess myocardial perfusion and viability.
myocardial perfusion imaging
Nuclear cardiology technique that evaluates blood flow to heart muscle using radioactive tracers.
myocardial viability assessment
Testing to determine whether dysfunctional cardiac tissue retains metabolic activity and may recover function after reva...
no-reflow
Impaired myocardial perfusion despite restoration of epicardial coronary flow after reperfusion therapy.
no-reflow phenomenon
Impaired myocardial perfusion despite successful epicardial coronary artery recanalization following PCI.
non-inferiority trial
A clinical trial design that aims to demonstrate a new treatment is not worse than standard therapy by more than a prede...
NSTEMI
Non-ST-elevation myocardial infarction, a type of heart attack diagnosed without characteristic ST-segment elevation on...
NT-proBNP
N-terminal pro b-type natriuretic peptide, a biomarker used for heart failure diagnosis and prognosis.
NYHA class
New York Heart Association functional classification system (I-IV) for heart failure symptom severity based on activity...
OCT
High-resolution intravascular imaging modality providing detailed visualization of coronary artery wall structure and st...
P-value
A statistical measure indicating the probability that observed results occurred by chance, with P<0.05 typically conside...
patient-oriented composite endpoint
A composite outcome measure that includes all-cause death, any myocardial infarction, and any revascularization.
patient-reported outcome measures
Standardized instruments capturing patient perspectives on symptoms, functional status, and quality of life without clin...
PCSK9 inhibitors
A class of cholesterol-lowering drugs that block proprotein convertase subtilisin/kexin type 9.