Neuromuscular Medicine Glossary

The functional unit of the neuromuscular system consisting of a motor neuron and all muscle fibers it innervates. Used i...

The electrical activity of a single motor unit recorded during needle electromyography examination.

Motor unit number estimation; electrophysiological technique used to quantify the number of functioning motor units in a...

Motor Unit Number Index, a neurophysiological technique for estimating motor unit numbers using surface EMG interference...

Motor unit action potentials with increased duration, amplitude, and phases, indicating chronic neurogenic changes. A ke...

Surgical procedure removing muscle tissue sample for microscopic examination and diagnosis.

Autoantibodies against muscle-specific kinase protein, found in seronegative myasthenia gravis with distinct clinical fe...

An autoimmune neuromuscular disorder characterized by weakness and fatigue of skeletal muscles. The condition involves a...

Life-threatening exacerbation of myasthenia gravis requiring mechanical ventilation due to respiratory muscle weakness.

Characteristic facial appearance in myasthenia gravis patients, featuring bilateral ptosis, weak facial expression, and...

Continuous involuntary muscle contractions producing a rippling or undulating appearance of the muscle surface.

Disease of muscle tissue causing weakness, typically with normal nerve function.

A regulatory protein essential for proper cardiac muscle contraction. Mutations cause hypertrophic cardiomyopathy and so...

Heterotopic bone formation within muscle tissue, typically following trauma or in genetic conditions. Creates characteri...

Delayed muscle relaxation after voluntary contraction, causing muscle stiffness. A key clinical finding in myotonic diso...

A characteristic electromyographic finding where muscle fibers fire repetitively after stimulation, producing a distinct...

An inherited multisystem disorder characterized by progressive muscle weakness and delayed muscle relaxation (myotonia).

Nerve conduction study measuring electrical conduction along peripheral nerves.

An inflammatory myopathy characterized by muscle fiber necrosis with minimal inflammatory infiltrate, associated with sp...

A recording electrode inserted into muscle tissue for electromyography, available in monopolar and concentric configurat...

Muscle wasting resulting from denervation, characterized by specific histological patterns including grouped fiber atrop...

Pain, numbness, or weakness in the legs that occurs with walking and is relieved by rest or flexion, caused by spinal st...

Synapse between motor neuron and muscle fiber where nerve signals trigger muscle contraction.

Impaired signal transmission between motor nerves and muscles at the neuromuscular junction.