Pediatric Pathology Glossary

Congenital brain malformation where the cerebral hemispheres fail to separate properly during development.

A severe fetal condition characterised by abnormal accumulation of fluid in at least two body compartments (e.g., pleura...

Brain injury in newborns caused by oxygen deprivation and reduced blood flow during the perinatal period.

A low-grade malignant spindle-cell tumour of infancy and early childhood harbouring the ETV6–NTRK3 fusion, associated wi...

The most common benign vascular tumour of infancy, characterised by a postnatal proliferative phase followed by spontane...

The International Neuroblastoma Pathology Classification; a standardised histopathological grading system for peripheral...

Abbreviation for International Neuroblastoma Risk Group, the pre-treatment risk stratification framework for neuroblasto...

A histopathological prognostic classification system for neuroblastic tumours stratifying them into favourable and unfav...

An international collaborative framework that provides a pre-treatment risk stratification system for neuroblastoma base...

A non-functioning segment of lung tissue lacking a normal bronchial connection, sharing the visceral pleura with adjacen...

An abnormally persistent focus of embryonic metanephric tissue located within the renal lobule, considered a precursor l...

Telescoping of one segment of bowel into an adjacent segment, causing obstruction and ischaemia; the most common cause o...

A rare locally aggressive vascular tumour of infancy and early childhood associated with the potentially fatal coagulopa...

A severe consumptive coagulopathy with profound thrombocytopenia caused by platelet and clotting factor trapping within...

A surgical procedure for biliary atresia in which a Roux-en-Y loop of jejunum is anastomosed to the porta hepatis to fac...

Neurological damage caused by severe neonatal jaundice resulting in bilirubin deposition in brain tissue.

A clonal proliferative disorder of Langerhans cells characterised by the accumulation of CD1a- and CD207 (langerin)-posi...

Acronym for Langerhans Cell Histiocytosis, a clonal myeloid neoplasm involving CD1a/CD207-positive Langerhans cells.

A sex cord–stromal tumour arising from testicular Leydig cells in children, often presenting with isosexual precocious p...

Rare brain malformation characterized by absent or reduced cerebral gyri resulting in a smooth brain surface.

A diffuse, multifocal proliferation of abnormal lymphatic channels involving multiple organ systems, classified under th...

Post-mortem softening, discolouration, and skin slippage of fetal tissues resulting from autolysis in utero after fetal...

Respiratory distress in newborns caused by inhalation of meconium-stained amniotic fluid.

The most common malignant brain tumour of childhood, arising in the cerebellum and classified by histological variant an...