Cancer Screening Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
HPV testing HPV
Molecular test that detects high-risk human papillomavirus strains associated with cervical cancer development.
co-testing
Simultaneous use of both cytology and HPV testing for cervical cancer screening in eligible age groups.
colonoscopy
Endoscopic examination of the large intestine using a flexible tube with a camera to screen for colorectal cancer.
colposcopy
A diagnostic procedure using a magnifying instrument to examine the cervix, vagina, and vulva for abnormal areas.
core needle biopsy
Minimally invasive tissue sampling procedure using a large-gauge needle to obtain tissue cores for histologic diagnosis...
cytology
Microscopic examination of individual cells to detect abnormal cellular changes indicative of cancer or precancer.
DCIS
Ductal carcinoma in situ; abnormal cells confined to breast milk ducts without invasion into surrounding tissue.
diagnostic workup
The series of examinations and tests performed to evaluate abnormal screening findings and establish a definitive diagno...
digital breast tomosynthesis
Three-dimensional mammography technique that creates multiple thin-slice images of the breast to improve cancer detectio...
digital mammography
A breast imaging technique using digital detectors instead of film to capture and store mammographic images.
double reading
Quality assurance practice where two radiologists independently interpret the same screening mammogram to improve cancer...
endoscopic mucosal resection
Advanced endoscopic technique for removing large flat or sessile colorectal polyps that cannot be safely excised by stan...
false positive
Screening test result that incorrectly indicates cancer presence when no cancer exists.
fecal immunochemical test
Colorectal cancer screening test that detects human hemoglobin in stool samples using antibody-based technology.
FIT
Fecal immunochemical test; a stool-based screening method for colorectal cancer that detects hidden blood.
FOBT
Non-invasive screening test that detects hidden blood in stool samples as an indicator of colorectal cancer.
GRADE
Systematic approach for rating the quality of evidence and strength of recommendations in clinical practice guidelines.
HEDIS
Healthcare quality measurement tool that includes cancer screening performance indicators used by health plans and provi...
heterogeneously dense
A breast tissue composition category indicating scattered fibroglandular densities that may obscure small masses on mamm...
high-grade squamous intraepithelial lesion
Bethesda System category indicating moderate to severe cervical dysplasia with significant potential for progression to...
HPV testing
Molecular test that detects high-risk human papillomavirus strains associated with cervical cancer development.
HSIL
Cytological finding indicating significant cervical cellular abnormalities with higher risk of progression to cancer if...
image-guided biopsy
A minimally invasive procedure using imaging guidance to obtain tissue samples from suspicious lesions identified during...
incidentaloma
An unexpected finding discovered during imaging performed for unrelated reasons, requiring clinical evaluation.
interval cancer
A cancer diagnosed between regular screening rounds, suggesting either rapid growth or screening failure.