Neurosurgical Oncology Glossary

A treatment-related inflammatory response that mimics tumor growth on imaging but represents tissue reaction rather than...

Delayed tissue death caused by radiation therapy, often difficult to distinguish from tumor recurrence on imaging.

Standardized grading system developed by the Radiation Therapy Oncology Group for assessing radiation-induced toxicity a...

Classification system for extent of meningioma resection, ranging from Grade I (complete with dural attachment) to Grade...

Minimally invasive tissue sampling procedure using computer-guided navigation for precise targeting.

A non-invasive radiation therapy technique delivering focused, high-dose radiation to brain tumors with submillimeter pr...

Standard treatment regimen combining radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed gli...

A benign WHO grade I tumor strongly associated with tuberous sclerosis complex, typically occurring near the foramen of...

Surgical removal of 90-99% of visible tumor tissue, leaving minimal residual disease.

A neurogenic region adjacent to the lateral ventricles implicated in glioma stem cell biology.

Surgical removal of tumor tissue beyond the contrast-enhancing margin to include surrounding brain tissue that may harbo...

Located above the tentorium cerebelli, referring to brain tumors or surgical procedures in the upper brain compartments.

Areas on T1-weighted MRI sequences that appear darker than surrounding brain tissue, often indicating tissue destruction...

An alkylating chemotherapy agent commonly used in treating glioblastoma and other brain tumors.

Advanced MRI technique that visualizes white matter fiber tracts to guide surgical planning and preserve neural pathways...

A distinct fibrous boundary that may surround certain brain tumors, facilitating complete surgical removal.

Surgical reduction of tumor volume when complete resection is not feasible, aimed at relieving symptoms and improving tr...

Histopathological classification system indicating the degree of malignancy and aggressiveness of brain tumors.

The complex cellular and molecular ecosystem surrounding tumor cells that influences growth and treatment response.

Documented growth or worsening of a tumor based on imaging or clinical criteria, distinct from pseudoprogression.

Apparent tumor enhancement on imaging that results from technical factors rather than true tumor vascularity.

Return or regrowth of neoplastic tissue following initial treatment, either at the original site or distant location.

A non-invasive therapy using low-intensity, intermediate-frequency electric fields to disrupt cancer cell division in gl...

The degree of blood vessel development within and around a brain tumor, affecting surgical approach and bleeding risk.