Neuroendocrinology Glossary

Hypothalamic region that produces oxytocin, vasopressin, and corticotropin-releasing hormone.

Small hypothalamic neurons that secrete releasing and inhibiting hormones into the hypothalamic-hypophyseal portal syste...

Post-translational modification of prohormones into bioactive peptide hormones through enzymatic cleavage and chemical m...

Targeted radiotherapy using radiolabeled somatostatin analogs for treating somatostatin receptor-positive neuroendocrine...

An intestinal hormone that reduces appetite and gastric motility, often dysregulated in neuroendocrine disorders.

Catecholamine-secreting tumor arising from chromaffin cells in the adrenal medulla.

A prohormone that yields multiple bioactive peptides including ACTH, β-endorphin, and melanocortin peptides.

An enzyme that cleaves prohormones into their active peptide forms within neuroendocrine cells.

A large precursor polypeptide that undergoes post-translational processing to yield multiple bioactive peptides includin...

Bioactive peptide molecules that modulate physiological processes through specific receptor interactions in neuroendocri...

Hypothalamic peptide hormones that stimulate the release of specific hormones from the anterior pituitary.

Syndrome of inappropriate antidiuretic hormone secretion causing hyponatremia.

Inhibitory peptide hormone that suppresses growth hormone release and has widespread regulatory effects throughout the b...

Presence and density of somatostatin receptors on neuroendocrine tumor cells, determining treatment eligibility and imag...

A nuclear medicine imaging technique using radiolabeled somatostatin analogs to detect neuroendocrine tumors.

Elevated prolactin levels resulting from psychological or physiological stress that activates hypothalamic-pituitary pat...

Master circadian pacemaker located in the hypothalamus that regulates biological rhythms.

Hypothalamic nucleus containing magnocellular neurons that produce oxytocin and vasopressin for posterior pituitary rele...

A synaptic vesicle glycoprotein used as an immunohistochemical marker for neuroendocrine differentiation.

Immunohistochemical marker used to identify neuroendocrine cells and confirm neuroendocrine tumor diagnosis.

Specialized ependymal cells in the hypothalamus that regulate hormone transport between cerebrospinal fluid and brain pa...

Hypothalamic tripeptide hormone that stimulates thyroid-stimulating hormone release from the anterior pituitary.

A dopaminergic neural pathway connecting the hypothalamus to the pituitary gland, primarily involved in prolactin regula...

Antidiuretic hormone that regulates water retention and blood pressure in the body.