Neuromodulation Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
Charge Density
The amount of electrical charge delivered per unit area of electrode surface, a critical safety parameter in neurostimulation.
Polarity Reversal
The programming technique of switching electrode polarity (anode/cathode) to modify stimulation field direction and cove...
Pulse Width
The duration of each electrical pulse in microseconds, a key programmable parameter in neurostimulation devices.
Pulsed Radiofrequency
A modified radiofrequency technique that delivers energy in brief pulses rather than continuously, creating neuromodulat...
Radiofrequency Ablation
A minimally invasive procedure using high-frequency electrical current to heat and destroy specific nerve tissue to inte...
Recruitment Threshold
Minimum stimulation intensity required to activate a sufficient population of neural fibers to produce therapeutic effec...
Refractory Epilepsy
Epilepsy that does not respond adequately to antiepileptic medications, often requiring alternative treatments such as n...
Responsive Neurostimulation
An adaptive neuromodulation system that detects abnormal brain activity and delivers targeted stimulation to prevent or...
Rheobase
The minimum electrical current intensity required to excite neural tissue with an infinitely long stimulus duration.
Sacral Neuromodulation
A therapeutic approach using electrical stimulation of sacral nerve roots to treat bladder, bowel, and pelvic floor dysf...
Sham Stimulation
A control condition in neuromodulation research where patients receive inactive or subtherapeutic stimulation to assess...
Spinal Cord Stimulator
Implantable device that delivers electrical pulses to the spinal cord to manage chronic pain conditions.
Stimulation Artifact
Electrical interference patterns generated by active neurostimulation that can obscure physiological signals during neur...
Stun Effect
Temporary worsening of symptoms immediately following neurostimulation device implantation, typically resolving as tissu...
Subthreshold Stimulation
Electrical stimulation delivered below the threshold for conscious sensation, used in modern neurostimulation paradigms.
Sweet Spot Programming
A programming approach that identifies the optimal electrode configuration and stimulation parameters that provide maxim...
Tachyphylaxis
Rapid loss of therapeutic response to neuromodulation therapy despite continued or increased stimulation parameters.
Therapeutic Efficacy Assessment
Systematic evaluation of neuromodulation therapy outcomes using standardized measures and patient-reported data.
Therapeutic Steering
The precise manipulation of electric field direction and intensity using multiple electrode contacts to optimize neural...
Therapeutic Washout
The gradual return of symptoms following discontinuation of neuromodulation therapy, used to assess treatment efficacy.
Therapeutic Window
The range of stimulation parameters between the threshold for therapeutic benefit and the onset of adverse side effects.
Therapy Cycling
Programmed alternation between periods of active stimulation and rest to prevent neural accommodation.
Tonic Stimulation
Continuous, regular-frequency neurostimulation typically delivered at 40-100 Hz for pain relief.
Transcranial Direct Current Stimulation
A non-invasive brain stimulation technique that applies weak electrical currents to modulate neuronal activity.
Transcranial Magnetic Stimulation
Non-invasive neuromodulation technique using magnetic fields to stimulate specific brain regions.