Gynecologic Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
ovarian preservation
Surgical approach that maintains ovarian function in reproductive-age patients when oncologically safe.
lymphadenectomy
Surgical removal of lymph nodes, performed for staging or therapeutic purposes in gynecologic cancers.
lymphovascular space invasion
Presence of tumor cells within lymphatic or blood vessels, indicating increased metastatic risk in gynecologic cancers.
microsatellite instability
Genetic marker indicating defective DNA mismatch repair, relevant for immunotherapy decisions.
mucinous adenocarcinoma
Ovarian cancer subtype producing mucin, often large and unilateral at presentation.
neoadjuvant chemotherapy
Systemic treatment administered before surgical intervention to reduce tumor burden.
omental caking
Thickening and nodularity of the omentum due to tumor infiltration.
omentectomy
Surgical removal of the omentum, routinely performed as part of staging procedures for ovarian and other gynecologic can...
optimal debulking
Surgical removal of tumor tissue leaving residual nodules ≤1 cm in diameter.
ovarian preservation
Surgical approach that maintains ovarian function in reproductive-age patients when oncologically safe.
papillary serous adenocarcinoma
Aggressive subtype of ovarian or endometrial cancer characterized by papillary growth pattern and serous differentiation...
para-aortic lymphadenectomy
Surgical removal of lymph nodes along the para-aortic region, performed as part of staging or therapeutic procedures in...
parametrial boost
Additional focused radiation dose delivered to the parametrial tissue in cervical cancer treatment to improve local cont...
parametrial involvement
Extension of cervical cancer into the lateral connective tissue surrounding the cervix and upper vagina.
parametrium
Connective tissue surrounding the cervix and upper vagina, frequently assessed for cancer extension in gynecologic malig...
PARP inhibitor
A class of targeted therapy drugs that block DNA repair enzymes, particularly effective in BRCA-mutated cancers.
pelvic exenteration
Extensive surgical procedure involving removal of pelvic organs, typically performed for advanced or recurrent gynecolog...
performance status
Standardized assessment of a cancer patient's functional capacity and ability to tolerate treatment.
peritoneal carcinomatosis
Widespread dissemination of cancer throughout the peritoneal cavity, commonly seen in advanced ovarian cancer.
peritoneal studding
Multiple small tumor implants scattered across the peritoneal surface, resembling studs or seeds.
peritoneal washing
Intraoperative cytological sampling procedure using saline irrigation to detect free cancer cells in the peritoneal cavi...
platinum-resistant
Cancer that progresses during or within six months of completing platinum-based chemotherapy treatment.
platinum-sensitive
Disease that recurs more than six months after completing platinum-based chemotherapy.
port site metastasis
Tumor recurrence at trocar insertion sites following laparoscopic surgery for cancer.
positive margins
Presence of tumor cells at the edge of surgically removed tissue, indicating incomplete excision.