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Head Neck Oncology Glossary

100 terms total — 24 showing — Last updated 15 Sep 2026

sentinel lymph node biopsy

Professional Technical IVT

Surgical technique to identify and remove the first lymph node draining a tumor site.

Showing 25–48 of 100

esthesioneuroblastoma

Professional Technical IVT

Rare malignant neuroectodermal tumor arising from the olfactory epithelium in the nasal cavity.

Technical Term Full entry →

extracapsular extension

Professional Technical IVT

Tumor growth beyond the capsule of a lymph node, indicating aggressive disease.

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fibula free flap

Advanced Technical IVT

Vascularized bone graft from the fibula used for mandibular reconstruction in head and neck cancer surgery.

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field cancerization

Advanced Technical IVT

Molecular concept describing widespread mucosal changes in the upper aerodigestive tract from carcinogenic exposure. Exp...

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first bite syndrome

Intermediate Technical IVT

Severe cramping pain in the parotid region with the first bite of each meal. Complication following surgery near the dee...

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free flap reconstruction

Professional Technical IVT

Surgical technique using tissue transfer with microvascular anastomosis to reconstruct defects after tumor resection.

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Frey syndrome

Intermediate Technical IVT

Abnormal sweating and flushing in the preauricular region during eating following parotidectomy. Results from aberrant n...

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glossectomy

Professional Technical IVT

Surgical removal of part or all of the tongue to treat oral cavity malignancies.

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hemilaryngectomy

Professional Technical IVT

Surgical removal of one half of the larynx while preserving voice and swallowing function.

Technical Term Full entry →

hemimandibulectomy

Advanced Technical IVT

Surgical removal of half of the mandible, typically performed for extensive mandibular tumors.

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Oropharyngeal squamous cell carcinoma associated with human papillomavirus infection, particularly HPV-16.

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hyoid bone suspension

Professional Technical IVT

Surgical technique to elevate and secure the hyoid bone, often used in airway reconstruction.

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hypoglossal nerve

Intermediate Technical IVT

Twelfth cranial nerve controlling tongue movement; injury causes tongue deviation and speech/swallowing difficulties.

Anatomical Term Full entry →

IMRT

Advanced Technical IVT

Advanced radiation therapy technique that modulates beam intensity to spare normal tissues while targeting tumors.

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infraorbital nerve

Intermediate Technical IVT

Branch of the maxillary division of the trigeminal nerve, often at risk during maxillofacial oncology surgery.

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internal jugular vein

Intermediate Technical IVT

Major cervical vein; sacrifice during radical neck dissection affects venous drainage and may cause complications.

Anatomical Term Full entry →

Karnofsky Performance Scale

Professional Technical IVT

Functional status assessment tool using percentage scores (0-100%) to evaluate cancer patient activity levels. Alternati...

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keratosis

Intermediate Technical IVT

Thickened, hyperkeratinized epithelial lesion that may represent premalignant change in head and neck mucosa.

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laryngectomy

Intermediate Technical IVT

Surgical removal of the larynx, typically performed for advanced laryngeal cancer.

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lymphangioma

Intermediate Technical IVT

Benign lymphatic malformation commonly occurring in the head and neck region, particularly in pediatric patients.

Technical Term Full entry →

lymphoepithelial carcinoma

Advanced Technical IVT

Undifferentiated nasopharyngeal carcinoma with prominent lymphoid infiltrate. Strongly associated with Epstein-Barr viru...

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lymphoscintigraphy

Professional Technical IVT

Nuclear medicine imaging study to map lymphatic drainage patterns.

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lymphovascular invasion

Advanced Technical IVT

Tumor cell penetration into lymphatic or blood vessels, indicating increased metastatic potential.

Technical Term Full entry →

marginal mandibular nerve

Intermediate Technical IVT

Branch of facial nerve controlling lower lip movement; injury causes asymmetric smile and lip incompetence.

Anatomical Term Full entry →
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