Neuro Oncology Glossary

Direct delivery of chemotherapy drugs into the cerebrospinal fluid via lumbar puncture or ventricular reservoir to treat...

Genetic alteration in IDH1 or IDH2 genes that serves as a key biomarker and therapeutic target in brain tumors.

A standardized assessment tool measuring a patient's functional status and ability to perform daily activities, crucial...

Cancer spread to the cerebrospinal fluid spaces and meningeal surfaces, also called carcinomatous meningitis, with poor...

Abnormal contrast enhancement of the brain and spinal cord surface membranes on MRI, often indicating tumor spread or in...

Damage to the brain's white matter, often appearing as treatment-related complications in neuro-oncology patients.

A rare embryonal brain tumor that arises from primitive neuroectodermal tissue, primarily affecting infants and young ch...

A typically benign tumor arising from the meninges, the protective membranes surrounding the brain and spinal cord.

DNA repair enzyme whose expression level affects response to alkylating chemotherapy agents in brain tumors.

A biomarker that predicts response to alkylating chemotherapy, requiring careful editorial attention to statistical repo...

Laboratory testing of tumor tissue for genetic and molecular markers that guide diagnosis, prognosis, and treatment sele...

Classification of brain tumors based on specific genetic and molecular characteristics rather than histological appearan...

A multidisciplinary conference that incorporates comprehensive molecular profiling data to guide personalized treatment...

The central nervous system pathway including the brain and spinal cord along which tumors can spread.

The spread of brain tumors along cerebrospinal fluid pathways throughout the central nervous system, including brain and...

Spread of tumor cells through cerebrospinal fluid pathways to distant sites within the central nervous system.

A rare, typically benign intraventricular brain tumor composed of neuronal and glial elements.

Comprehensive evaluation of cognitive function used to assess brain tumor effects on mental abilities.

A type of brain tumor arising from oligodendrocytes, characterized by fried-egg appearance on histology and often carryi...

An implanted ventricular access device consisting of a catheter and subcutaneous dome, used for CSF sampling and intrath...

A three-drug chemotherapy regimen combining procarbazine, CCNU (lomustine), and vincristine, standard treatment for olig...

MRI technique that measures blood flow characteristics in brain tissue to assess tumor vascularity and treatment respons...

MRI technique that measures blood flow and vascular characteristics within brain tissue to assess tumor vascularity.

Increased metabolic activity in brain tissue surrounding a tumor or treatment site, often detected on PET imaging and di...