Ocular Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
tumor calcification
Calcium deposits within ocular tumors that appear as hyperechoic foci on ultrasound and aid in differential diagnosis.
diffuse infiltrating retinoblastoma
Rare variant of retinoblastoma characterized by flat growth pattern without discrete mass formation, often mimicking inf...
dosimetric planning
Computational process of calculating radiation dose distribution for ocular brachytherapy treatments.
endophytic growth
Tumor growth pattern extending inward toward the vitreous cavity. Critical for staging and treatment planning in retinob...
enucleation
Surgical removal of the entire eyeball while preserving the extraocular muscles and orbital tissues.
episcleral plaque therapy
Targeted radiation treatment using radioactive plaques surgically attached to the eye's outer surface to treat intraocul...
epithelioid cell melanoma
Aggressive subtype of uveal melanoma characterized by large, polygonal cells with poor prognosis.
exenteration
Radical surgical removal of all orbital contents including the eye, extraocular muscles, fat, and sometimes eyelids, per...
exophytic growth
Tumor growth pattern extending outward from the retinal surface into the vitreous cavity.
Flexner-Wintersteiner rosettes
Pathognomonic histological structures in retinoblastoma characterized by radially arranged cells around a central lumen....
FNAB
Fine needle aspiration biopsy, a diagnostic procedure to obtain tissue samples from ocular tumors.
Fuchs adenoma
A benign hyperplastic lesion of the ciliary epithelium, typically appearing as a cystic or solid mass in the pars plicat...
fundus autofluorescence
Non-invasive imaging technique that detects natural fluorescence from retinal tissues, useful for evaluating choroidal l...
gamma knife radiosurgery
Stereotactic radiosurgery technique using focused gamma rays for precise treatment of small orbital and optic pathway tu...
GEP
Gene Expression Profile testing used to assess metastatic risk in uveal melanoma patients.
globe salvage
Treatment approach aimed at preserving the eye while achieving local tumor control in intraocular malignancies.
globe-sparing therapy
Treatment approaches that preserve the eye while managing intraocular tumors. Includes radiation therapy, local resectio...
intraocular lymphoma
Primary or secondary lymphoma affecting intraocular structures, most commonly vitreoretinal lymphoma presenting as uveit...
intraocular pressure spike
Acute elevation in eye pressure often following tumor-related procedures or treatment. Requires immediate monitoring and...
iodine-125 plaque
Radioactive episcleral applicator containing I-125 seeds used for localized tumor irradiation. Standard treatment for me...
iridocyclectomy
Surgical procedure involving excision of iris and ciliary body tissue, typically for localized anterior uveal tumors.
iris mammillations
Small, nodular growths on the iris surface that may indicate iris melanoma or serve as a risk factor for malignant trans...
juxtapapillary location
An anatomical descriptor for tumors located within 1-2 disc diameters of the optic nerve head, presenting unique managem...
LBD
Largest basal diameter, a critical measurement for staging and treatment planning of intraocular tumors.
Lenaerts syndrome
A rare oculo-cerebral syndrome characterized by bilateral diffuse uveal melanocytic proliferation associated with centra...