Ocular Oncology Glossary

Ultrasonographic characteristic of choroidal melanomas showing reduced internal reflectivity. Distinguished from solid e...

The American Joint Committee on Cancer staging system used for standardized classification of ocular tumors.

Unpigmented variant of ocular melanoma that lacks the characteristic dark coloration, making diagnosis more challenging.

Diagnostic procedure involving aspiration of aqueous humor for cytological or molecular analysis. Used in suspected intr...

BRCA1-associated protein 1, a tumor suppressor gene whose mutations are associated with aggressive uveal melanoma and po...

A form of radiation therapy using radioactive sources placed directly on or within the eye to treat ocular tumors.

Disruption of the membrane between the retina and choroid, often indicating aggressive tumor growth in ocular oncology.

Calcium deposits overlying choroidal melanomas, appearing as bright echogenic foci on ultrasonography. Important differe...

Systemic chemotherapy used to reduce tumor size in retinoblastoma, often enabling globe-preserving treatments.

An abnormal depression or concavity in the choroidal surface, which may be associated with overlying retinal pigment epi...

The most common primary intraocular malignancy in adults, arising from melanocytes in the choroidal layer of the eye.

A benign pigmented lesion of the choroid that requires monitoring for potential malignant transformation.

A malignant melanocytic tumor arising from the ciliary body portion of the uveal tract.

Benign vascular tumor of the choroid appearing as a well-demarcated orange-red lesion with characteristic imaging featur...

Yellowish retinal deposits resembling those in Coats disease, often associated with retinoblastoma. May mask underlying...

Alternative reference to COMS, the landmark multi-center randomized clinical trial that established treatment standards...

Landmark multi-center clinical trial that established treatment protocols for choroidal and ciliary body melanomas.

A distinctive tumor morphology characterized by a narrow neck connecting intraocular and extraocular tumor components th...

Collaborative Ocular Melanoma Study - a landmark randomized clinical trial that established treatment standards for chor...

Pre-malignant condition of the conjunctiva characterized by abnormal epithelial cell proliferation without basement memb...

A malignant lymphoid tumor affecting the conjunctival tissue, often presenting as a salmon-pink mass.

A malignant melanocytic tumor of the conjunctiva with high potential for local recurrence and systemic metastasis.

Laser treatment targeting the ciliary body to reduce intraocular pressure, used in tumor-related glaucoma.

Laboratory examination of tumor chromosomes to identify genetic abnormalities that predict prognosis and guide treatment...