Pediatric Rheumatology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
cytokine storm syndrome CSS
A life-threatening hyperinflammatory condition characterized by excessive immune activation and cytokine release, often complicating systemic juvenile arthritis.
joint contracture
Fixed reduction in joint range of motion resulting from chronic inflammation, fibrosis, or muscle weakness in pediatric...
JSLE
Juvenile-onset Systemic Lupus Erythematosus, referring to systemic lupus erythematosus with onset before age 18.
Juvenile Arthritis Multidimensional Assessment Report
A comprehensive assessment tool measuring disease activity and quality of life in pediatric rheumatic diseases.
juvenile dermatomyositis
A rare inflammatory muscle disease in children characterized by proximal weakness and distinctive skin rashes.
juvenile idiopathic arthritis
The most common chronic rheumatic disease in children, characterized by persistent joint inflammation of unknown cause.
juvenile spondyloarthritis
A group of inflammatory arthritides affecting children, primarily involving the spine and entheses.
juvenile systemic sclerosis
Rare autoimmune connective tissue disorder causing skin thickening and organ involvement in children.
Kawasaki disease
Acute systemic vasculitis primarily affecting children under five years of age.
leg length discrepancy
Difference in limb length that can occur in children with chronic knee inflammation due to altered growth patterns.
linear scleroderma
A form of localized scleroderma presenting as linear bands of thickened skin, often affecting limbs and potentially caus...
lipodystrophy
Loss of subcutaneous fat tissue, a potential complication of juvenile dermatomyositis or calcinosis.
localized scleroderma
A pediatric autoimmune connective tissue disorder causing skin and subcutaneous tissue thickening without systemic organ...
macrophage activation syndrome
A life-threatening complication of systemic JIA characterized by excessive immune activation and cytokine storm.
mechanic's hands
Hyperkeratotic, cracked skin on the radial and palmar aspects of fingers seen in juvenile dermatomyositis.
methotrexate intolerance
A clinical syndrome involving gastrointestinal and behavioral symptoms that develop in pediatric patients receiving meth...
micrognathia
Underdevelopment of the jaw, particularly the mandible, often occurring in juvenile idiopathic arthritis affecting the t...
minimal change nephritis
A form of kidney involvement in pediatric lupus characterized by mild histologic changes but potentially significant pro...
morning stiffness duration
The length of time joint stiffness persists after awakening, used as a key clinical parameter for assessing inflammatory...
muscle enzyme panel
A set of laboratory tests measuring enzymes released from damaged muscle tissue, used to assess inflammatory myopathy se...
myositis-specific antibodies
Autoantibodies specifically associated with inflammatory myopathies in children.
nailfold capillaroscopy
Non-invasive imaging technique to evaluate microvascular changes at the nailfold.
NOMID
Neonatal-Onset Multisystem Inflammatory Disease, the most severe form of cryopyrin-associated periodic syndrome.
oligoarticular
Affecting four or fewer joints during the first six months of disease, a key subtype classification in pediatric arthrit...
oligoextension
The progression of oligoarticular juvenile idiopathic arthritis to involve five or more joints within the first six mont...