Pediatric Rheumatology Glossary

Having detectable antinuclear antibodies, a significant risk factor for chronic anterior uveitis in juvenile idiopathic...

A recombinant human interleukin-1 receptor antagonist used to treat autoinflammatory conditions and systemic juvenile id...

Antibodies against cyclic citrullinated peptides, used as a diagnostic marker in rheumatoid arthritis.

Autoantibodies against histidyl-tRNA synthetase, associated with inflammatory myopathy and interstitial lung disease in...

Autoantibodies against cardiolipin, a phospholipid component of cell membranes, often tested in pediatric lupus evaluati...

Imaging procedure using contrast material to visualize joint structures and guide injections.

Loss of joint cartilage thickness due to inflammatory damage, detectable on imaging and indicating potential for permane...

A group of hereditary disorders characterized by recurrent episodes of systemic inflammation without high-titer autoanti...

A high-intensity treatment approach using the patient's own hematopoietic stem cells after conditioning therapy for seve...

Advanced disease-modifying medications derived from living organisms, used for refractory pediatric rheumatic diseases.

A rare monogenic autoinflammatory disorder causing granulomatous arthritis, dermatitis, and uveitis in children.

Temporary treatment used to maintain disease control while transitioning between long-term therapies.

Abnormally low levels of complement component C3, often indicating complement consumption in pediatric autoimmune diseas...

Abnormal calcium phosphate deposits in soft tissues, a serious complication of juvenile dermatomyositis.

A fully human monoclonal antibody targeting interleukin-1β, used in pediatric autoinflammatory and rheumatic diseases.

Cryopyrin-Associated Periodic Syndromes, a group of autoinflammatory disorders caused by mutations in the NLRP3 gene.

A North American research database collecting standardized data on pediatric rheumatic diseases for clinical studies.

The Childhood Health Assessment Questionnaire, a validated parent-reported outcome measure for functional assessment in...

A standardized disability index scoring component of the Childhood Health Assessment Questionnaire used to measure funct...

A validated instrument measuring functional disability and health status in children with rheumatic diseases.

Silent eye inflammation commonly associated with oligoarticular JIA, requiring regular screening due to absence of sympt...

The clinical Juvenile Arthritis Disease Activity Score, a modified version that excludes laboratory markers for disease...

Chronic Nonbacterial Osteomyelitis, a sterile inflammatory bone condition affecting children and adolescents.

Non-infectious inflammatory bone disorder primarily affecting children and adolescents.