Psychopharmacology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
loading dose
An initial higher dose given to rapidly achieve therapeutic drug levels.
adjuvant therapy
Additional medication used alongside primary psychiatric treatment to enhance effectiveness.
agonist
Medication that activates receptors to produce a biological response.
AIMS
Abnormal Involuntary Movement Scale, a standardized rating scale used to monitor for tardive dyskinesia in patients taki...
akathisia
A movement disorder characterized by subjective restlessness and compulsive need to move, often caused by antipsychotic...
akineisia
Complete or near-complete loss of voluntary movement, often presenting as severe motor slowing in psychiatric patients.
allosteric modulation
Indirect drug action where compounds bind to sites other than the primary receptor binding site to alter receptor functi...
anhedonia
The inability to experience pleasure in activities that were previously enjoyable, a core symptom of depression.
anticholinergic
Describes effects or agents that block acetylcholine receptors, often causing dry mouth, constipation, and cognitive imp...
anticholinergic burden
Cumulative effect of multiple medications with anticholinergic properties, increasing risk of cognitive impairment and o...
anticholinergic toxicity
Syndrome resulting from excessive blockade of acetylcholine receptors, characterized by 'hot as a hare, blind as a bat,...
antimuscarinic
Type of anticholinergic drug that specifically blocks muscarinic acetylcholine receptors.
antipsychotic-induced parkinsonism
Motor disorder characterized by tremor, rigidity, and bradykinesia caused by dopamine receptor blockade from antipsychot...
atypical antipsychotic
Second-generation antipsychotic medications with reduced risk of movement disorders compared to older agents.
augmentation therapy
The addition of a second medication to enhance the effectiveness of a primary psychiatric medication that has shown part...
benzodiazepine
A class of psychoactive drugs primarily used for anxiety, sleep disorders, and seizures, known for their potential for d...
benztropine
Anticholinergic medication used to treat extrapyramidal side effects caused by antipsychotic drugs, particularly acute d...
bioavailability
The proportion of an administered drug that reaches systemic circulation and is available for therapeutic action.
black box warning
The FDA's strongest warning for prescription medications, highlighting serious or life-threatening risks.
breakthrough depression
Return of depressive symptoms during ongoing antidepressant treatment, indicating incomplete response or treatment resis...
breakthrough symptom
Return of psychiatric symptoms despite ongoing medication treatment, indicating need for adjustment.
CGIS
Clinical Global Impression Scale for Schizophrenia, a rating instrument used to assess overall illness severity and trea...
cholinesterase inhibitor
Medication that blocks acetylcholine breakdown, used in dementia treatment and to counteract anticholinergic effects.
clozapine monitoring
Mandatory laboratory surveillance program required for patients taking clozapine to detect potentially fatal blood disor...
cognitive enhancer
Medication designed to improve cognitive functions such as memory, attention, or executive function.