Cardiometabolic Medicine Glossary

Cellular damage caused by excessive lipid accumulation in non-adipose tissues.

Major adverse cardiovascular events, a composite endpoint used in clinical trials.

The ability to switch between glucose and fat oxidation based on nutrient availability and metabolic demands.

Cluster of cardiovascular risk factors including central obesity, dyslipidemia, and insulin resistance.

The presence of small amounts of albumin in urine, serving as an early marker of kidney damage and cardiovascular risk i...

Maturity-Onset Diabetes of the Young, a monogenic form of diabetes caused by mutations in genes affecting beta-cell func...

The cardiac muscle's utilization of glucose as a metabolic substrate, altered in diabetic cardiomyopathy.

A liver condition characterized by fat accumulation in hepatocytes without significant alcohol consumption, commonly ass...

Non-alcoholic steatohepatitis, an advanced form of fatty liver disease with inflammation.

New-onset diabetes, referring to diabetes diagnosed during hospitalization or acute illness. Important distinction from...

New-onset diabetes mellitus, often used interchangeably with NOD but may specifically refer to post-transplant or medica...

Non-ST-elevation myocardial infarction, a type of AMI without ST elevation on ECG. Management strategy depends on risk s...

Injectable cholesterol-lowering medication that blocks PCSK9 protein function.

Non-invasive technique measuring arterial pulse wave changes to assess endothelial function.

Blood glucose levels measured after eating, typically assessed 2 hours after meal consumption to evaluate glucose tolera...

Post-transplant diabetes mellitus, a form of new-onset diabetes occurring after organ transplantation. Often related to...

Pulse wave velocity, a measure of arterial stiffness that increases with age and cardiometabolic disease. Higher PWV val...

Cholesterol content of triglyceride-rich lipoproteins after lipolysis, increasingly recognized as atherogenic.

Antidiabetic medication that blocks glucose reabsorption in the kidney.

Rebound hyperglycemia following nocturnal hypoglycemia, caused by counter-regulatory hormone response to low blood sugar...

ST-elevation myocardial infarction, a type of AMI requiring emergency reperfusion therapy. Diabetic patients with STEMI...

Percentage of time glucose levels remain within target range, typically 70-180 mg/dL.

Thrombolysis in Myocardial Infarction risk score, used for risk stratification in acute coronary syndromes. Different ve...

Thiazolidinedione, an insulin-sensitizing antidiabetic medication class.