Cardiovascular Research Glossary

Dual antiplatelet therapy combining aspirin with a P2Y12 inhibitor to prevent thrombotic events after percutaneous coron...

Angiographically confirmed complete occlusion or flow-limiting thrombus within or adjacent to a previously implanted ste...

Achievement of successful deployment and positioning of a medical device (such as a stent) according to predefined techn...

Standardized composite outcome measure in cardiovascular device trials combining cardiac death, target vessel myocardial...

Blood clot formation specifically associated with implanted cardiac devices such as stents or mechanical valves.

The interval from hospital arrival to first balloon inflation during primary PCI for STEMI patients.

Angioplasty balloon catheter coated with antiproliferative medication that transfers drug directly to vessel wall during...

An independent committee that monitors clinical trial safety data and makes recommendations regarding trial continuation...

The percentage of blood pumped out of the left ventricle with each heartbeat, commonly used as a measure of cardiac func...

The systematic review and classification of potential clinical endpoints by independent experts to ensure consistent and...

Hemodynamic measurement assessing the functional significance of coronary stenosis during maximal hyperemia.

Invasive physiologic measurement comparing distal coronary pressure to aortic pressure during maximal hyperemia to asses...

An international ethical and scientific quality standard for designing, conducting, recording, and reporting clinical tr...

Echocardiographic measure of left ventricular systolic function assessing myocardial deformation during contraction usin...

A validated risk stratification tool for predicting in-hospital and post-discharge mortality in patients with acute coro...

A measure of treatment effect in time-to-event analyses, comparing the instantaneous risk of events between treatment gr...

The study of blood flow dynamics and pressures within the cardiovascular system.

Heart failure with preserved ejection fraction, a clinical syndrome characterized by symptoms of heart failure despite n...

Heart failure with reduced ejection fraction, defined as ejection fraction ≤40% with signs and symptoms of heart failure...

Re-narrowing of a coronary artery within or adjacent to a previously implanted stent, typically defined as >50% diameter...

The process of providing potential research participants with comprehensive information about a study to enable voluntar...

A resting coronary physiology index that assesses functional significance of coronary stenosis without pharmacological v...

An analysis principle that includes all randomized participants in their originally assigned treatment groups, regardles...

Pre-planned statistical evaluation of trial data before study completion, often used for safety monitoring or efficacy a...