Endocrine Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
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A rare functional neuroendocrine tumor secreting vasoactive intestinal peptide, causing watery diarrhea syndrome.
cytoreduction surgery
Surgical approach aimed at reducing tumor burden in patients with metastatic neuroendocrine tumors.
dedifferentiation
Process where well-differentiated neuroendocrine tumors transform into poorly differentiated or anaplastic forms.
desmoplastic reaction
Fibrous tissue response surrounding neuroendocrine tumors, particularly common in small bowel primaries.
DOTANOC
A somatostatin receptor imaging agent used in PET scans for neuroendocrine tumor detection and staging.
DOTATATE
A radiolabeled somatostatin analog used in both imaging and therapy of neuroendocrine tumors.
endoscopic ultrasound-guided biopsy
Minimally invasive procedure using endoscopic ultrasound to guide tissue sampling of pancreatic and other gastrointestin...
ENETS
European Neuroendocrine Tumor Society, which provides staging and treatment guidelines for neuroendocrine tumors.
enterochromaffin cell
Specialized neuroendocrine cells in the gastrointestinal tract that produce serotonin and other hormones.
everolimus
An mTOR inhibitor medication used to treat advanced neuroendocrine tumors.
extrathyroidal extension
Invasion of thyroid cancer beyond the thyroid capsule into surrounding neck structures.
Fine Needle Aspiration Biopsy
A minimally invasive procedure to obtain cellular samples from thyroid nodules for cytological examination.
functional imaging
Imaging techniques that assess metabolic activity and receptor expression rather than purely anatomical structures in en...
Functional NET
A neuroendocrine tumor that produces clinically significant amounts of hormones causing recognizable symptoms.
G3 neuroendocrine carcinoma
High-grade neuroendocrine neoplasm with Ki-67 proliferation index >20% and aggressive clinical behavior.
Gallium-68 DOTATOC
A radiolabeled somatostatin analog used in positron emission tomography for imaging neuroendocrine tumors.
gastric NET
A neuroendocrine tumor arising in the stomach, classified into distinct subtypes based on underlying pathophysiology.
gastrinoma
A neuroendocrine tumor that secretes gastrin, causing Zollinger-Ellison syndrome.
glucagonoma
A rare functional pancreatic neuroendocrine tumor that secretes excessive amounts of glucagon hormone.
hepatic arterial embolization
Interventional procedure that blocks blood supply to liver metastases from neuroendocrine tumors.
Hurthle Cell Carcinoma
A variant of follicular thyroid cancer characterized by cells with abundant eosinophilic cytoplasm and distinct mitochon...
Ileal NET
A neuroendocrine tumor arising from the terminal small bowel, the most common location for small intestinal NETs.
indeterminate thyroid nodule
Thyroid nodule with cytological features that cannot be definitively classified as benign or malignant on fine needle as...
insulinoma
A pancreatic neuroendocrine tumor that secretes excessive insulin, causing hypoglycemia.
iodine-avid
Describing thyroid tissue or tumors that actively concentrate radioactive iodine, making them suitable for radioiodine t...