Endocrine Oncology Glossary

A proliferation marker used to grade neuroendocrine tumors based on percentage of dividing cells.

A long-acting somatostatin receptor agonist used in the treatment of neuroendocrine tumors and acromegaly.

Surgical removal of one lobe of the thyroid gland, typically performed for unilateral thyroid disease.

The anatomical region containing lymph nodes at highest risk for metastasis from thyroid cancer.

A neuroendocrine tumor arising from thyroid parafollicular C cells that secrete calcitonin.

A hereditary syndrome causing multiple endocrine neoplasia affecting parathyroid, pancreas, and pituitary glands.

Multiple endocrine neoplasia type 2, an inherited syndrome predisposing to medullary thyroid carcinoma and pheochromocyt...

Nuclear medicine imaging using meta-iodobenzylguanidine to detect and localize catecholamine-secreting tumors.

The number of mitotic figures per unit area in histologic examination, used for grading neuroendocrine tumors.

An intermediate histologic grade for neuroendocrine tumors with moderate proliferative activity and intermediate prognos...

Genetic analysis of thyroid nodule samples to improve diagnostic accuracy and guide treatment decisions.

Presence of multiple, separate tumor foci within the same organ or tissue, commonly seen in thyroid and pancreatic neuro...

Grade 1 neuroendocrine tumor with low proliferation rate and indolent behavior, defined by specific histological criteri...

A cancer arising from neuroendocrine cells that can secrete hormones and occur throughout the body.

A glycolytic enzyme used as a serum biomarker and immunohistochemical marker for neuroendocrine tumors.

A synthetic somatostatin analog medication used to treat neuroendocrine tumors and related symptoms.

A neuroendocrine tumor arising from hormone-producing cells within the pancreatic islets of Langerhans.

A rare neuroendocrine tumor arising from paraganglia in various body locations outside the adrenal medulla.

Nuclear medicine imaging technique using radiolabeled somatostatin analogs to detect neuroendocrine tumors.

A targeted radiotherapy using radiolabeled somatostatin analogs to treat neuroendocrine tumors expressing somatostatin r...

A neuroendocrine tumor of the adrenal medulla that secretes catecholamines.

Blood test measuring catecholamine metabolites, the preferred screening method for pheochromocytoma and paraganglioma di...

A histologic grade indicating high-grade neuroendocrine tumors with aggressive behavior and poor prognosis.

Surgical removal of the thyroid gland in asymptomatic individuals at high genetic risk for developing medullary thyroid...