Hematologic Oncology Glossary

A preparative treatment protocol administered before stem cell transplantation to eliminate malignant cells and suppress...

Intensive treatment given after initial remission to eliminate remaining cancer cells and prevent relapse.

A laboratory test that detects antibodies attached to red blood cell surfaces or circulating in plasma.

A chemotherapy drug commonly used in the treatment of acute leukemias and some lymphomas, also known as ara-C.

The study of chromosomes and chromosomal abnormalities, essential for hematologic malignancy classification and prognosi...

Acute systemic inflammatory response caused by massive cytokine release, often following immunotherapy.

Severe inflammatory response characterized by excessive cytokine release. Life-threatening complication requiring immedi...

Treatment aimed at reducing the number of abnormal cells in the blood or bone marrow before definitive therapy.

A monoclonal antibody targeting CD38 used in multiple myeloma treatment, administered intravenously or subcutaneously.

Five-point scale for interpreting PET scan response in lymphoma patients. Standard imaging assessment tool.

The most common type of non-Hodgkin lymphoma, characterized by large B-cell lymphoid cells that grow diffusely throughou...

Abnormal cellular morphology indicating disordered development or maturation in hematopoietic cells.

Standardized scale measuring patient functional status and ability to perform daily activities, crucial for treatment pl...

The process by which transplanted stem cells establish themselves in the bone marrow and begin producing new blood cells...

A myeloproliferative neoplasm characterized by persistent elevation of platelet counts and megakaryocyte hyperplasia in...

Cancer involvement outside the bone marrow, occurring in organs or tissues not typically involved.

Blood cell production outside bone marrow, occurring in myelofibrosis and other conditions. Compensatory mechanism for m...

A medical emergency characterized by fever in the setting of severe neutropenia, indicating high risk for life-threateni...

Fluorescence in situ hybridization test used to detect chromosomal abnormalities in hematologic cancers. Essential for d...

A laboratory technique used to analyze and sort cells based on their physical and chemical characteristics for hematolog...

An indolent B-cell lymphoma characterized by a follicular growth pattern and typically following a slowly progressive cl...

A potentially life-threatening complication following bone marrow or stem cell transplantation where donor cells attack...

The beneficial immunologic reaction where donor immune cells recognize and eliminate residual malignant cells in the rec...

A rare B-cell malignancy characterized by lymphocytes with distinctive cytoplasmic projections resembling hairs.