Pediatric Nephrology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
detrusor-sphincter dyssynergia DSD
Neurogenic condition where the bladder muscle and external urethral sphincter contract simultaneously instead of coordinating properly.
DMSA scan
Nuclear medicine imaging using dimercaptosuccinic acid to assess kidney scarring and differential renal function.
eGFR
A calculated measure of kidney function based on serum creatinine, age, sex, and race. Used to stage chronic kidney dise...
electrolyte imbalance
Abnormal levels of essential minerals in blood, commonly involving sodium, potassium, or phosphate in pediatric kidney d...
ESKD
The final stage of chronic kidney disease requiring renal replacement therapy. Replaces the older term 'end-stage renal...
ESRD
End-stage renal disease requiring renal replacement therapy in pediatric patients.
Fanconi syndrome
A generalized dysfunction of the proximal renal tubules resulting in multiple transport defects and wasting of various s...
fluid overload
Excess fluid accumulation in the body due to impaired kidney function or excessive fluid intake. Particularly concerning...
FSGS
A pattern of kidney damage affecting parts of some glomeruli, commonly causing nephrotic syndrome in children.
Gitelman syndrome
A hereditary salt-losing nephropathy causing hypomagnesemia and hypocalciuria in children and adolescents.
glomerular filtration rate
A measure of kidney function indicating how much blood the kidneys filter per minute, critical for assessing renal impai...
glomerular sclerosis
Pathological hardening and scarring of glomerular tissue leading to permanent loss of kidney filtering units.
growth velocity
Rate of linear growth measured over time, particularly important in monitoring children with chronic kidney disease.
hematuria
Presence of blood in urine, which may be visible (gross) or microscopic, indicating possible kidney or urinary tract pat...
hemodialysis
A renal replacement therapy that filters blood through an external machine to remove waste products and excess fluid.
hemolytic uremic syndrome
A thrombotic microangiopathy characterized by the triad of hemolytic anemia, thrombocytopenia, and acute kidney injury,...
Henoch-Schönlein purpura
An IgA-mediated vasculitis affecting small vessels, commonly causing nephritis in children along with skin, joint, and g...
horseshoe kidney
Congenital fusion of the lower poles of both kidneys, creating a horseshoe-shaped organ.
hydronephrosis
Dilation of the kidney's collecting system due to impaired urine outflow or vesicoureteral reflux.
hypercalciuria
Excessive calcium excretion in urine that can lead to kidney stone formation and nephrocalcinosis in children.
hyperkalemia
Abnormally high levels of potassium in the blood, potentially causing dangerous cardiac arrhythmias.
hypertensive nephrosclerosis
Kidney damage caused by chronic hypertension, characterized by arteriolar sclerosis and progressive renal function decli...
hyponatremic dehydration
Fluid loss with disproportionate sodium depletion, commonly seen in infants with gastroenteritis or renal salt-wasting c...
hypospadias
Congenital condition where the urethral opening is located on the underside of the penis rather than at the tip.
IgA nephropathy
The most common primary glomerulonephritis worldwide, characterized by IgA deposits in kidney glomeruli.