Cardiometabolic Medicine Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
VADT study VADT
Veterans Affairs trial examining intensive versus standard glucose control in type 2 diabetes.
CGM
Continuous glucose monitoring device that tracks interstitial glucose levels in real-time.
CIMT
Carotid intima-media thickness, a non-invasive marker of subclinical atherosclerosis measured by ultrasound. Used to ass...
coronary artery calcium score
A CT-based measurement of calcium deposits in coronary arteries used to assess atherosclerotic burden and cardiovascular...
coronary flow reserve
Ratio of maximal coronary blood flow during vasodilation to resting coronary flow, measuring coronary microvascular func...
CREDENCE trial
Landmark renal outcomes trial demonstrating kidney protective effects of canagliflozin in diabetic kidney disease.
DAPA-HF trial
Heart failure outcomes trial demonstrating benefits of dapagliflozin in patients with heart failure with reduced ejectio...
dawn phenomenon
The natural rise in blood glucose levels in the early morning hours due to hormonal changes, particularly problematic in...
DCCT
Landmark trial demonstrating that intensive glucose control reduces diabetic complications in type 1 diabetes.
DECLARE-TIMI 58
Large cardiovascular outcomes trial that demonstrated cardiovascular safety of dapagliflozin in patients with type 2 dia...
diabetic cardiomyopathy
Heart muscle disease that occurs in diabetic patients independent of coronary artery disease or hypertension.
diabetic ketoacidosis
A serious acute complication of diabetes characterized by hyperglycemia, ketosis, and metabolic acidosis.
DPP-4 inhibitor
A class of oral antidiabetic medications that enhance incretin hormone activity by blocking the enzyme responsible for t...
dual glucose sensor
Continuous glucose monitoring system using two sensors simultaneously for enhanced accuracy and reliability.
ectopic fat deposition
Abnormal accumulation of fat in organs not designed for fat storage, such as liver, muscle, and heart.
EDIC study
Observational follow-up to DCCT demonstrating long-term benefits of early intensive glucose control.
eGFR
Calculated estimate of kidney function based on serum creatinine and demographic factors.
EMPA-REG OUTCOME
Pivotal cardiovascular outcomes trial that first demonstrated cardiovascular benefits of SGLT2 inhibitors.
EMPEROR-Reduced
Heart failure outcomes trial demonstrating cardiovascular benefits of empagliflozin in heart failure with reduced ejecti...
endothelial dysfunction
Impaired function of the blood vessel lining that contributes to cardiovascular disease in diabetes.
euglycemic ketoacidosis
A life-threatening condition characterized by ketoacidosis with normal or only mildly elevated blood glucose levels, oft...
flow-mediated dilation
A non-invasive ultrasound test measuring endothelial function by assessing brachial artery dilation in response to incre...
FMD
Flow-mediated dilation, a non-invasive measure of endothelial function using brachial artery ultrasound. Impaired FMD in...
fractional glucose utilization
Measure of the proportion of glucose uptake that occurs through insulin-dependent pathways in metabolic assessment.
FRS
Framingham Risk Score, a validated tool for estimating 10-year cardiovascular disease risk.