Gynecologic Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
ovarian preservation
Surgical approach that maintains ovarian function in reproductive-age patients when oncologically safe.
ascites
Abnormal accumulation of fluid in the peritoneal cavity, commonly associated with advanced ovarian cancer.
bevacizumab
Monoclonal antibody drug that inhibits blood vessel formation in tumors by targeting VEGF.
bilateral oophorectomy
Surgical removal of both ovaries, performed for treatment or prevention of gynecologic cancers or as part of comprehensi...
borderline ovarian tumor
Low-grade epithelial ovarian neoplasm with malignant potential but lacking stromal invasion.
bowel anastomosis
Surgical connection of two segments of bowel following resection during gynecologic oncology procedures.
brachytherapy
Radiation therapy delivered by placing radioactive sources directly into or near tumor tissue, commonly used for cervica...
BRCA mutation
Hereditary genetic alteration in BRCA1 or BRCA2 genes that significantly increases risk of breast and ovarian cancers.
CA-125
A protein biomarker used to monitor ovarian cancer, elevated levels may indicate disease presence or recurrence.
carcinomatosis
Widespread dissemination of cancer cells throughout a body cavity, typically the peritoneum.
cervical conization
Surgical removal of a cone-shaped portion of cervical tissue for diagnosis or treatment.
cervical intraepithelial neoplasia
Precancerous changes in cervical epithelial cells graded as CIN 1, CIN 2, or CIN 3 based on severity.
cervical stenosis
Narrowing or closure of the cervical canal, which can occur following radiation therapy or surgical procedures, potentia...
chemorefractory
Describing cancer that shows no response to initial chemotherapy treatment, indicating primary drug resistance.
chemosensitivity
The degree to which cancer cells respond to chemotherapy treatment, affecting treatment selection and prognosis.
chemotherapy-induced peripheral neuropathy
Nerve damage affecting hands and feet caused by neurotoxic chemotherapy agents.
cisplatin
Platinum-based chemotherapy agent that is a cornerstone of treatment for gynecologic cancers, particularly cervical and...
clear cell carcinoma
Histologic subtype of ovarian cancer characterized by cells with clear cytoplasm and poor prognosis.
colposcopy
Diagnostic procedure using a magnifying instrument to examine the cervix, vagina, and vulva for abnormal tissue.
consolidation therapy
Additional treatment given after primary therapy to maintain response and prevent recurrence, commonly used in ovarian c...
cytoreductive surgery
Surgical procedure to remove as much visible tumor as possible, typically performed in ovarian cancer treatment.
diaphragmatic stripping
Surgical technique involving removal of peritoneal deposits from the diaphragm surface during cytoreductive surgery.
dose-dense chemotherapy
Treatment schedule that delivers chemotherapy cycles at shorter intervals than standard protocols.
endocervical curettage
Surgical scraping of the endocervical canal to obtain tissue samples for histological examination.
endometrial biopsy
Diagnostic procedure involving sampling of endometrial tissue to detect malignancy or pre-malignant conditions.