Gynecologic Oncology Glossary

Abnormal thickening of the endometrial lining that may progress to malignancy if untreated.

Rare malignant tumor arising from endometrial stromal cells, typically presenting with abnormal uterine bleeding.

Ultrasound measurement of the endometrial lining thickness, used to assess risk of endometrial pathology in postmenopaus...

A type of endometrial cancer that resembles normal endometrial glands and is typically estrogen-related.

Conservative surgical approaches that preserve reproductive organs and function while treating gynecologic cancers in yo...

International standardized system for classifying the extent and spread of gynecologic cancers.

Rapid intraoperative histopathological examination of tissue samples to guide immediate surgical decisions.

Inherited genetic alteration present in all cells that can predispose to cancer development.

Group of pregnancy-related tumors arising from placental trophoblastic tissue, including molar pregnancies and choriocar...

Landmark clinical trial that established the role of bevacizumab in combination with carboplatin and paclitaxel for adva...

Standardized scale used by the Gynecologic Oncology Group to assess a patient's functional capacity and ability to toler...

Clinical trial framework developed by the Gynecologic Oncology Group for standardizing cancer research and treatment.

Rare ovarian cancer arising from stromal cells, often producing estrogen and associated with endometrial hyperplasia.

Tumor marker protein (Human Epididymis Protein 4) elevated in ovarian cancer, used alongside CA-125 for diagnosis and mo...

Inherited genetic condition that significantly increases the lifetime risk of developing certain cancers.

Heated intraperitoneal chemotherapy administered during surgery for peritoneal malignancies.

Laboratory analysis to detect homologous recombination deficiency in tumors, used to guide PARP inhibitor therapy.

Heated chemotherapy delivered directly into the peritoneal cavity during surgery.

Laboratory technique using antibodies to identify specific proteins in tissue samples for cancer diagnosis and classific...

Cytoreductive surgery performed after initial chemotherapy cycles in ovarian cancer treatment.

Rapid pathologic examination of tissue samples during surgery to guide immediate surgical decision-making in gynecologic...

Direct delivery of chemotherapy into the peritoneal cavity to maximize local drug concentration.

Metastatic ovarian tumor, typically from gastrointestinal primary malignancies, characterized by signet ring cells.

Outpatient surgical technique using electrified wire loop to remove abnormal cervical tissue for treatment and diagnosis...