Neurosurgical Oncology Glossary

Cancer spread to the pia mater and arachnoid membranes surrounding the brain and spinal cord, causing neurological dysfu...

An alkylating chemotherapy agent used in brain tumor treatment, particularly for recurrent gliomas and medulloepitheliom...

A tumor arising from the meningeal coverings of the brain and spinal cord, typically benign but occasionally malignant.

A molecular marker indicating DNA repair gene silencing that predicts favorable response to alkylating chemotherapy in b...

Displacement of brain structures from their normal central position, typically due to mass effect from tumor, edema, or...

Genetic and biochemical characteristics of tumor tissue that provide diagnostic, prognostic, and therapeutic guidance.

Comprehensive genetic and molecular analysis of tumor tissue to guide treatment decisions and prognosis.

Classification of brain tumors based on genetic and molecular characteristics rather than solely on histological appeara...

Treatment administered before primary surgical intervention to reduce tumor size, improve resectability, or target micro...

The central nervous system comprising the brain and spinal cord as a functional unit.

The spread of tumor cells through cerebrospinal fluid pathways to distant sites within the central nervous system.

Fine fibrillary processes observed in certain brain tumors, particularly helpful in diagnosing oligodendrogliomas.

A primary brain tumor arising from oligodendrocytes, characterized by distinctive histological features and genetic mark...

An implanted ventricular access device used for intrathecal drug delivery or CSF sampling.

Surgical technique combining tumor resection with immediate reconstruction to restore normal anatomy and function.

A chemotherapy protocol combining three agents commonly used for treating oligodendroglial tumors.

Increased metabolic activity in brain tissue surrounding a tumor, often indicating infiltrative growth or inflammation.

The brain tissue immediately surrounding a tumor that may contain infiltrating cancer cells or be affected by tumor-rela...

Seizures occurring before, during, or shortly after neurosurgical procedures, requiring specific management protocols.

Fluid accumulation in brain tissue surrounding a tumor, causing mass effect and neurological symptoms.

The brain tissue immediately surrounding a tumor, which may contain infiltrating tumor cells and treatment effects.

A benign WHO grade I astrocytic tumor most commonly occurring in children, typically in the cerebellum and optic pathway...

Increased signal intensity on MRI after gadolinium contrast administration, indicating blood-brain barrier breakdown.

A postoperative complication following posterior fossa surgery characterized by mutism, ataxia, and behavioral changes.