Breast Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
Oncotype DX
Genomic test that analyzes tumor genes to predict chemotherapy benefit and recurrence risk.
PARP inhibitor
A targeted therapy drug that blocks poly ADP-ribose polymerase enzymes, particularly effective in BRCA-mutated breast ca...
partial mastectomy
Surgical removal of the tumor and a margin of surrounding normal tissue while preserving most of the breast.
pathological complete response
Absence of invasive cancer in breast and lymph nodes after neoadjuvant treatment.
pCR
Abbreviation for pathological complete response, indicating no residual cancer after treatment.
peau d'orange
A clinical sign characterized by skin dimpling resembling an orange peel, typically associated with inflammatory breast...
phyllodes tumor
A rare fibroepithelial breast tumor with leaf-like microscopic architecture, classified as benign, borderline, or malign...
progesterone receptor
A protein found in breast cancer cells that can bind to the hormone progesterone and influence tumor growth and treatmen...
radiation boost
Additional focused radiation dose delivered to the tumor bed after whole-breast irradiation to reduce local recurrence r...
radioguided occult lesion localization
A surgical technique using radioactive seed placement to guide excision of non-palpable breast lesions.
reactive lymphadenopathy
Enlargement of lymph nodes due to benign inflammatory response rather than malignant involvement.
recurrence score
A numerical value from genomic tests predicting breast cancer recurrence risk and chemotherapy benefit.
residual disease
Remaining tumor tissue found at surgical resection after completion of neoadjuvant therapy, indicating incomplete respon...
sentinel lymph node biopsy
Surgical procedure to examine the first lymph node where cancer is likely to spread from the primary tumor.
skin-sparing mastectomy
Mastectomy technique that preserves the breast skin envelope while removing breast tissue and nipple-areola complex.
SLNB
Abbreviation for sentinel lymph node biopsy, a surgical staging procedure.
specimen radiography
Immediate X-ray imaging of surgically excised breast tissue to confirm removal of targeted lesion.
surgical clips
Small metallic markers placed in the tumor bed during breast-conserving surgery to mark the location for radiation thera...
surgical margin
The distance between the edge of removed tumor and the boundary of excised tissue.
T-stage
The tumor size component of TNM staging system for breast cancer classification.
tamoxifen
A selective estrogen receptor modulator used as hormone therapy for estrogen receptor-positive breast cancer.
tissue expander
Inflatable implant device used to gradually stretch chest tissue after mastectomy in preparation for permanent breast re...
TNBC
Abbreviation for triple-negative breast cancer.
triple-negative breast cancer
Breast cancer subtype lacking estrogen receptors, progesterone receptors, and HER2 protein overexpression.
tumor bed
Anatomical site where breast tumor was located, marked for radiation therapy planning after surgical excision.