Endocrine Oncology Glossary

A targeted radiotherapy treatment for somatostatin receptor-positive neuroendocrine tumors.

Treatment using radioactive iodine (I-131) to destroy residual thyroid tissue or metastatic thyroid cancer cells.

Thyroid cancer that no longer concentrates radioactive iodine or progresses despite adequate radioiodine therapy.

Response Evaluation Criteria in Solid Tumors used to assess treatment response in neuroendocrine tumor clinical trials.

A branch of the vagus nerve that innervates most laryngeal muscles and is at risk during thyroid surgery.

Assessment of lymph node involvement in endocrine tumors to determine extent of disease and guide treatment decisions.

Genetic alteration in the SDHA gene encoding succinate dehydrogenase subunit A, associated with hereditary paraganglioma...

A genetic alteration in the succinate dehydrogenase complex iron sulfur subunit B gene associated with hereditary paraga...

Watery diarrhea caused by active secretion of electrolytes and water, characteristic of certain functional neuroendocrin...

Surveillance, Epidemiology, and End Results staging system used specifically for neuroendocrine tumors to classify exten...

A synthetic medication that mimics somatostatin hormone, used to treat functional neuroendocrine tumors.

Nuclear medicine imaging using radiolabeled somatostatin analogs to detect and stage neuroendocrine tumors.

A rare functional neuroendocrine tumor secreting somatostatin, often causing diabetes and gallbladder dysfunction.

Thyroglobulin levels measured after TSH stimulation to enhance sensitivity for detecting thyroid cancer recurrence.

A neuroendocrine marker protein used in immunohistochemistry to diagnose and classify neuroendocrine tumors.

Treatment approach using drugs that specifically target molecular pathways altered in neuroendocrine tumors.

An oral alkylating chemotherapy agent used in treating pancreatic neuroendocrine tumors, often combined with capecitabin...

A protein produced by thyroid follicular cells, used as a tumor marker for thyroid cancer recurrence after thyroidectomy...

The reduction of thyroglobulin levels to undetectable ranges following thyroidectomy and radioactive iodine therapy in t...

An autoimmune inflammatory condition affecting the extraocular muscles and orbital tissues, commonly associated with Gra...

Deliberate discontinuation of thyroid hormone replacement to stimulate TSH production for enhanced radioiodine therapy o...

A life-threatening hypermetabolic crisis representing the most severe manifestation of thyrotoxicosis.

Antibodies that mimic TSH action by binding to TSH receptors, causing hyperthyroidism in Graves' disease.

A characteristic histologic architecture of neuroendocrine tumors showing cells arranged in ribbon-like or cord patterns...