Neurosurgical Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
bevacizumab
Monoclonal antibody targeting VEGF used as anti-angiogenic therapy for recurrent glioblastoma.
eloquent brain
Brain regions responsible for critical neurological functions whose damage would result in significant permanent disabil...
eloquent cortex
Brain regions responsible for critical functions like speech, movement, or sensation that require special consideration...
eloquent white matter
White matter tracts essential for critical neurological functions such as motor, sensory, language, or visual processing...
en plaque meningioma
A meningioma variant that grows as a flat, carpet-like sheet rather than a discrete mass.
enhancing lesion
A brain abnormality that shows increased signal intensity after contrast agent administration on MRI, indicating blood-b...
ependymoma
A brain tumor arising from ependymal cells lining the ventricular system and central canal of the spinal cord.
extent of resection
Measure of how much tumor tissue was surgically removed, typically categorized as gross total, subtotal, or biopsy only.
FLAIR sequence
MRI imaging sequence that suppresses cerebrospinal fluid signal to enhance visualization of brain pathology adjacent to...
frameless stereotaxy
Image-guided surgical navigation system using surface landmarks rather than a fixed stereotactic frame.
functional mapping
Intraoperative techniques used to identify and preserve critical brain functions during neurosurgical procedures.
gamma knife
A stereotactic radiosurgery device that delivers highly focused radiation beams to treat brain tumors and other intracra...
ganglioglioma
A low-grade mixed neuronal-glial tumor typically presenting with seizures and commonly found in the temporal lobe.
Gliadel wafer
Biodegradable polymer wafer containing carmustine chemotherapy, implanted in the tumor cavity during surgery.
glioblastoma multiforme
The most aggressive form of primary brain tumor, requiring precise terminology in clinical documentation.
gross total resection
Complete surgical removal of all visible tumor tissue, distinguished from subtotal resection in surgical reports.
hemispherectomy
Surgical removal of one cerebral hemisphere, typically performed for intractable epilepsy or extensive hemispheric tumor...
hydrocephalus
Abnormal accumulation of cerebrospinal fluid within the brain ventricles, causing ventricular dilation and increased int...
hyperfractionated radiotherapy
A radiation therapy technique delivering multiple smaller doses per day to increase the total dose while potentially red...
IDH mutation
A genetic alteration in isocitrate dehydrogenase genes that defines distinct molecular subgroups of gliomas with prognos...
infratentorial
Located below the tentorium cerebelli, referring to brain tumors or surgical procedures in the posterior fossa.
intramedullary tumor
A tumor arising within the substance of the spinal cord parenchyma, as opposed to extramedullary locations.
intraoperative MRI
Real-time magnetic resonance imaging performed during brain surgery to guide tumor resection and assess completeness.
Karnofsky Performance Scale
A standardized assessment tool measuring a patient's functional status and ability to perform daily activities, scored f...
laser interstitial thermal therapy
Minimally invasive procedure using laser energy to heat and destroy tumor tissue under MRI guidance.