Pediatric Rheumatology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
cytokine storm syndrome CSS
A life-threatening hyperinflammatory condition characterized by excessive immune activation and cytokine release, often complicating systemic juvenile arthritis.
pannus formation
Development of inflammatory granulation tissue that invades and destroys joint cartilage and bone in chronic pediatric a...
patient-reported outcome measures
Standardized questionnaires completed by patients or parents to assess symptoms, function, and quality of life from the...
pediatric lupus
Systemic lupus erythematosus occurring in children, typically presenting with more severe disease than adult-onset lupus...
Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis
A periodic fever syndrome characterized by recurrent episodes of fever with oral ulcers, sore throat, and swollen lymph...
PFAPA syndrome
A periodic fever syndrome characterized by recurrent episodes of fever, aphthous stomatitis, pharyngitis, and cervical a...
PGA
Physician Global Assessment, a standardized visual analog scale used to rate overall disease activity in pediatric rheum...
polyarticular RF-negative
A JIA subtype affecting five or more joints with negative rheumatoid factor, typically having better prognosis than RF-p...
polyarticular RF-positive
A subtype of juvenile idiopathic arthritis affecting five or more joints with positive rheumatoid factor testing.
power Doppler ultrasound
An ultrasound technique that detects blood flow within inflamed synovial tissue, used to assess joint inflammation in pe...
psoriatic arthritis
A subtype of juvenile idiopathic arthritis associated with psoriasis or family history of psoriasis.
Raynaud's phenomenon
Vasospastic disorder causing color changes in digits in response to cold or stress.
sacroiliitis
Inflammation of the sacroiliac joints connecting the pelvis to the spine.
Shawl sign
A cutaneous manifestation of juvenile dermatomyositis affecting the shoulders and upper back.
Sjögren's syndrome
An autoimmune exocrinopathy causing dry eyes and mouth, rarely occurring as primary disease in children but associated w...
subclinical synovitis
Joint inflammation detectable only by imaging (ultrasound or MRI) without obvious clinical signs on physical examination...
subcutaneous calcinosis
Abnormal calcium and phosphate deposits in subcutaneous tissues, a potential complication of juvenile inflammatory myopa...
subcutaneous panniculitis-like T-cell lymphoma
A rare form of cutaneous lymphoma that can mimic autoimmune panniculitis and present as part of hemophagocytic lymphohis...
synovial fluid analysis
Laboratory examination of joint fluid to aid in diagnosis of arthritis and joint infections.
synovial hypertrophy
Thickening and proliferation of the synovial membrane lining joints, commonly seen in chronic pediatric arthritis condit...
systemic onset JIA
A severe subtype of juvenile arthritis characterized by high fever, rash, and systemic inflammation preceding joint invo...
temporomandibular joint involvement
Inflammation of the jaw joints in pediatric arthritis, often asymptomatic but potentially causing growth disturbances an...
tenosynovitis
Inflammation of the synovial sheath surrounding tendons, commonly affecting hands and feet in pediatric inflammatory art...
tocilizumab
A humanized monoclonal antibody targeting the interleukin-6 receptor, used in systemic juvenile idiopathic arthritis and...
tofacitinib
An oral JAK inhibitor approved for treatment of polyarticular course juvenile idiopathic arthritis in children.